The usage of GLP-1 medications, such as Semaglutide, continues to grow as can be shown by the hundreds of studies seen at www.clinicaltrials.gov and all the discussions on social media. 

Patients may prefer a compounded formulation of Semaglutide for sublingual administration because it is a no-needle, no-refrigeration, cost-effective option. However, not all sublingual compounds are created the same. In situations where the drug has a high molecular weight, such as Semaglutide, a base with the qualities of SubMagna® HMW, could be a good fit.

When attempting to maximize potential success of compounded sublingual medications, Semaglutide or otherwise, consider the following:

• Appropriate prepping of the mouth (oral cavity), which would reflect flossing, brushing your teeth, then swishing with warm water to make the mucosal area as receptive as it can be for sublingual delivery of a medication,
• Apply dose and leave in the mouth for a minimum of 5 minutes (longer if able), and
• Not drinking anything for 30-60 minutes (if you can still “taste” the flavor of the compound, often spearmint-peppermint, you still have Semaglutide in your mouth which would mean it could still be absorbing)

When it comes to sublingual compounded delivery – demand SubMagna® HMW.